He’s going to need to serve his prison sentence so this is a dangerous, crazy, moot point. They got him on State charges for what Cohen did and he ain’t gonna sing so time for Mr. Big to pay his debt to society, something he hopefully can’t escape again despite his moral and neurological bankruptcy

Tired of everyone dancing around this “small” problem. He has to be punished and it was stupid of society to let it get this bad. Fucking age limits, no older than 70 and mental competency tests that have teeth. Tax returns must be produced. Courts have enforced timelines for grave politico-legal issues. Emoluments safeguards enforced vigorously. No more profiting off using your own venues.

We have much to learn and improve on, Trump has exposed it all

Not so much for stocks, I mean like a better UI spreadsheet client that allows them to go to any period and see ledgers that are intuitively rendered and that lets them sort of experiment with the numbers so they can learn to maneuver things better. Like all their accounts, bills/recurring, paycheques, purchases. All rendered and projected or archived for easy traversal

Its like GTD: get everything out and externalized in an independant system or locus of reference and it takes most of the anxiety and human error out of it

I really hope they can get a partnership with a good forecasting app to set these kids up with forever so they can always project their finances and see how their choices affect the numbers

That would be one of the most helpful things to facillitate this

He should prove it by drinking some

Full disclosure: I have some unhealthty fantasies about DeSanctimonius being exorcised and renewed in the blood of the cleansing waters of Ganges river

You’re never gonna fully attnuate all the edge cases and it doesn’t really matter that some people end up being “allergic” or oversensitive or undersensitive to it. Thats what titration and medical supervision are for, not everything works for everyone.

Thats why choice and second/third/fourth line etc treatments exist. I sometimes do wonder if you did a double blind with folks and didn’t tell them, I would conjecture the hyper-extended nature of such things if that were so established could be sufficient to mitigate for individual differences in metabolic-polymorphism or whatever

Gotta dispose of them like how they do the fractional mountains of drugs

All these stalling tactics need to be mitigated and the Supreme Court needs to have an enforced timeline (maybe AI or at least legislatively established) for any case and moreso for questions of enormous gravity like presidents being able to murder political opponents without worry of criminal accountabillity.

Also, wtf are these paperless orders? How the fuck can Trump appeal time after time all the way up and down and the prosecution can’t bring up a recusal request for such extended judicial malice?

The point I’m making is, while I’m aware of people being fast or slow metabolizers, that should only factor in when it comes to active ingredient that is fully mechanically released and available for metabolism.

It cannot metabolize that which has not either been a) mechanically released or b) that which is pharmacodynamically inertt since it requires cleaving off the other binding substance (like l-lysine in Vyvanse) before the underlying active drug can be mechanically available to metabolize if that makes sense.

Vyvanse cannot be injected or administered in basically any other ROA than oral like normal dex because it (lis-dexamferamine—not dextroamphetamine) is inert until it has undergone the uncleaving of lysine from the active drug. Doesn’t matter how fast one metabolizes dextro, nobody metabolizes lis as a straight stimulant, it is inert until made not so thru the blood or whatever.

Also, doesn’t that mostly apply to codeine and morphine, wasn’t aware of that extending to oxy and hydro?

I don’t worship them I simply get surprised time to time altho maybe I should read their full dissents to get a better idea

XR/Extended Release

I’m very surprised the pharmaceutical market hasn’t produced the opioid analogue to Vyvanse requiring enzymatic conversion as opposed to mechanical release -> long lasting natural extended release mechanism. Its a great idea that hasn’t seemed to expand to many other therapeutic agents

Do you honestly believe folks like Jackson are equivalent to people like Thomas/Alito beyond their legal pedigree? You think she wants what they do?

Kagan, Jackson, Sotomayor are usually referred to as the liberal justices, aren’t they? Not sure whatchu getting at?

Also, why are you referring to them as Mullahs, they’re not religious teachers, any of them

But why are the liberal justices falling for it?

[old AIPAC name] He owes me money!

—AIPAC

Wanna talk about it, Sport 🥸

Tobi really is a lonely creep tho. Sometimes Michael goes way too far, and its ironic because they’re not super different in terms of being socially awkward and loners

How so?

Like Larry David is way funnier

In its current form its already nothing, its sets the price tag at $6 billion to addict the nation and start nouveau Opium wars and still get to keep a commi$h and get out of jail free for their service

Again $6 billion is nothing, thats $120 million per 1/50 states, how much is even gonna go to each survivor or does the government annex it all basically, add it to the pork barrel to be distributed amongst their “tru$ted” partners/affiliates?