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Joined 1 year ago
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Cake day: June 13th, 2023

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  • Full results from the study, presented at the American Heart Association annual scientific meeting in Philadelphia and published in the New England Journal of Medicine, suggest the drug has other beneficial effects beyond the known health benefits from losing weight.

    The heart risk difference between patients who received Wegovy, known chemically as semaglutide, and those on placebo began to appear almost immediately after starting treatment, researchers said.

    So it’s not just from losing weight!

    The associated risk factors include inflammation, blood pressure and blood sugar control, all of which can impact heart health.

    Patients on Wegovy experienced decreases in C-reactive proteins, an indication of inflammation, similar to those reported with cholesterol lowering statins, which are known to significantly lower heart risks, researchers reported.

    That is really promising!






  • For me it was playing Life is Strange for the first time. I bought it because it had been listed on Steam as “Overwhelmingly Positive” for ages, and at the time I was really enjoying the story-based games that companies like Telltale were producing. So, knowing nothing about the game, I picked it up and started playing it.

    The first act was slow. What I didn’t realize at the time was that the writers were establishing Arcadia Bay, a city in the Pacific Northwest, as a character. All the people in it needed to be recognizable, so it took time for them to teach the player about who they were, what mattered to them, how they fit in to the city, and what their flaws were. I actually stopped playing for a while after the first act. But, luckily, I picked it back up over the holiday season.

    I still remember playing it in my living room. I was so thoroughly absorbed into the story that when something tense happened in the second act and I couldn’t stop it the way I normally could, I was literally crushing the controller as if I could make things work by pulling the triggers harder.

    I am decidedly not the demographic that Life is Strange was written to appeal to, but they did such a good job writing a compelling story that it didn’t matter. I got sucked in, the characters became important to me, and I could not. put. it. down. I played straight through a night until I finished it.

    (If you’ve played it and you’re wondering, I chose the town the first time I played it.)

    I’ll never forget that game. I’ll also never forget the communities that spawned around it. I read the accounts of people who had just played it for the first time for about a year because it helped me relive the experience I had when I played it. It was incredible.



  • I am so torn on this. On the one hand, this is sorely needed. Not everyone in an organization is aware that information they feed to an LLM is often fed back into the LLM to train it, or that the LLM reflects bias in its training material, or even that an LLM might return false information. A strong policy is important to help communicate these things.

    On the other hand, LLMs have had the biggest impact on my productivity, well, ever. The speed with which I can write complex documents, write code, or help someone else solve a problem has been increased by an order of magnitude. My organization recently enacted something similar to this executive order, prohibiting the use of LLMs. Now I can't get those advantages at work anymore. I'm afraid a heavy-handed policy would effectively strip government workers of the same capabilities.





  • I’ve just spent a few weeks continually enhancing a script in a language I’m not all that familiar with, exclusively using ChatGPT 4. The experience leaves a LOT to be desired.

    The first few prompts are nothing short of amazing. You go from blank page to something that mostly works in a few seconds. Inevitably, though, something needs to change. That’s where things start to go awry.

    You’ll get a few changes in, and things will be going well. Then you’ll ask for another change, and the resulting code will eliminate one of your earlier changes. For example, I asked ChatGPT to write a quick python script that does fuzzy matching. I wanted to feed it a list of filenames from a file and have it find the closest match on my hard drive. I asked for a progress bar, which it added. By the time I was done having it generate code, the progress bar had been removed a couple of times, and changed out for a different progress bar at least three times. (On the bright side, I now know of multiple progress bar solutions in Python!)

    If you continue on long enough, the “memory” of ChatGPT isn’t sufficient to remember everything you’ve been doing. You get to a point where you need to feed it your script very frequently to give it the context it needs to answer a question or implement a change.

    And on top of all that, it doesn’t often implement the best change. In one instance, I wanted it to write a function that would parse a CSV, count up duplicate values in a particular field, and add that value to each row of the CSV. I could tell right away that the first solution was not an efficient way to accomplish the task. I had to question ChatGPT in another prompt about whether it was efficient. (I was soundly impressed that it recognized the problem after I brought it up and gave me something that ended up being quite fast and efficient.)

    Moral of the story: you can’t do this effectively without an understanding of computer science.






  • This is the one group that seems perpetually pissed off about everything, all the time, even getting things they wanted and asked for

    This is so true! One thing I’ve always loved about American liberal culture (yeah, I know; we’re not really liberal here) is that we laugh at our mistakes. For most of my life, Cable and Late Night comedy shows have been helping us find the humor in the things we would otherwise be enraged about. I feel like it has helped me stay sane all these years. I kind of feel bad for the Fox News-watching conservatives who spend their days oscillating from outrage to fear to outrage again. It must be hell on their cardiovascular health.