I thought it was just (or mostly) partial pressure of O2 when it comes to hemoglobin? It's been about 15 years since I was in school so I might remember wrong.
"Carbon dioxide increases hydrogen ion concentration and lowers tissue pH. As a consequence, hemoglobin’s affinity for oxygen decreases and oxygen release to tissues is facilitated."
There's another factor involved to convince the iron to let go of the oxygen, so if we mimicked that as well, then yes. It's just chemical reactions.
I thought it was just (or mostly) partial pressure of O2 when it comes to hemoglobin? It's been about 15 years since I was in school so I might remember wrong.
"Carbon dioxide increases hydrogen ion concentration and lowers tissue pH. As a consequence, hemoglobin’s affinity for oxygen decreases and oxygen release to tissues is facilitated."
https://www.medmastery.com/guides/blood-gas-analysis-clinical-guide/what-factors-affect-hemoglobins-oxygen-affinity