So I've recently taken an interest in these three distros:
All of these offer something very interesting:
Access to (basically) all Linux-capable software, no matter from what repo.
Both NixOS and blendOS are based on config files, from which your system is basically derived from, and Vanilla OS uses a package manager apx to install from any given repo, regardless of distribution.
While I've looked into Fedora Silverblue, that distro is limited to only install Flatpaks (edit: no, not really), which is fine for "apps", but seems to be more of a problem with managing system- and CLI tools.
I haven't distro hopped yet, as I'm still on Manjaro GNOME on my devices.
What are your thoughts on the three distros mentioned above?
Which ones are the most interesting, and for what reasons?
Personally, I'm mostly interested in NixOS & blendOS, as I believe they may have more advantages compared to Arch;
What do you think?
It depends on if the changes needs it or not. You can set a reboot flag on a given task and at the end the system will reboot, but if no reboot is needed then it will just make the change live.