Ha ha so true. I thought you were joking but you never know with the internet.
Ha ha so true. I thought you were joking but you never know with the internet.
Slightly educated guess medical opinion here?
As far as risk is concerned:
Smoke>>>vape>nothing.
Vaping will definitely have adverse effects we start cataloging more in 10-30 years. My guess? Likely some form of lung disease (maybe more of a restrictive pattern due to the microparticles in vapes—I could see if being like silicosis or pneumoconioses) and some forms of cancer.
I mean you basically don’t smoke then. Most of the effects of smoking are based on pack-years, which is the number of years you’ve smoked a pack per day. So two packs a day for 10 years? 20 pack years.
You have barely any pack years, and you stopped so young that the adverse effects are definitely reversed (10 years of cessation to reverse risk of lung CA/COPD).
Ones I’ve experienced because of healthcare and would’ve otherwise not really known about—
US tech CT Tech Xray Tech Medical Simulation Tech/Actor (this varies, can also be IT. Med sim centers need a ton of IT) ECMO Perfusionist
There are already a lot of good answers but I want to highlight this. Chronic tobacco smoke causes increased aging due to multiple mechanisms. Moreover, environmental tobacco exposure from second hand and third hand smoke prior to the 1990s was MASSIVE. So even if you didn’t smoke you got insane daily exposures to the same chemicals.
My comment was mostly intended as a joke (like me being bullish is going to make the market move in the other direction), but I do think that what happened in 2020 was artificially can-kicked down the road by unprecedented government intervention in the market. So it’s less of a “severe as I’d like” scenario and more of a “curtailed by massive global intervention in the economy.” Maybe that staved it off forever and we will have a soft landing? Possible, but I don’t think so.
We’ve been due for a recession since 2020–the drastic pullback for several months at the onset of COVID was hardly a “recession,” more like a blip. I’ve finally stopped saying it’s imminently going to happen, which maybe means it’s going to happen now.
The internet is such a funny place.
Open Lemmy and see this on the front page today with a ton of upvotes, yet I make a post a while back criticizing Boomers and my account gets brigaded and spammed. Hope that’s not happening to you OP!
Lemmy is almost as toxic as Reddit these days.
House of Dragons was actually pretty good. Reminded me of the beginning of GOT. Not sure if it’s continuing, though. But at least it’s a prequel so the plot points are all already out there in his history prequel books.
Yep, been saying this for years.
We know he told the show creators huge future plot points. That ending was the ending, it sucked, he’s embarrassed, the series will never be finished.
Honestly pretty much all through complex scenes and groupings in the app. I have different scenes for morning, late afternoon, and night. They all vary based on mood and season. That’s pretty much it. Only use automation for outside lights and to mimic presence when traveling.
I said this too—the Hue system is game changing as a mood setter. Helps me relax at night by dimming, etc.
I think in some ways that could work.
I think a better one may be fish living in a tank that suddenly had its filter break (fish being the brain, and the filter being the BBB).
Not exactly—although an MRI w/wout contrast may show some microvascular ischemia or cortical volume loss. Based on the study there may be some clues from secondary inflammatory markers, but those aren’t specific (other things can elevate them beyond long COVID).
I think this will likely remain a clinical diagnosis for several years until we understand more.
Bringing in a medical perspective since there is a lot of subtle misunderstanding in the comments section:
The source study is not referring to “brain bleeding” or “mini strokes” as a cause of long COVID—the results point more towards a breakdown of the integrity of the blood brain barrier and maybe micro vascular ischemia.
You can essentially think of your central nervous system (brain and spinal cord) as being surrounded by a very selective security system called the Blood Brain Barrier (BBB). The BBB exists to prevent certain chemicals and cell signaling molecules from entering the central nervous system and messing things up. Neurons and many of the cells that support neurons do not regenerate and tolerate stress as well as other parts of the body, which is why the BBB is so important. Through the various assays the primary authors used it seems like in the setting of long COVID there is a breakdown of the BBB—it starts letting things in and out that it shouldn’t be. This leads to inflammation and damage in the brain which likely results in immediate decreased processing ability and also long-term damage (which further leads to decreased processing ability). One of the components which “leaks” in this setting of BBB breakdown are components of the coagulation cascade (the things that make blood clot) which may potentiate small areas of clotting and decreased blood flow (a thing we called micro vascular ischemia—like an ischemic stroke but in very small capillaries). This entire mechanism is similar to (but very different in nuance) “leaky gut syndrome,” where the gut endothelium starts to break down and cause inflammation. I put that out there since leaky gut is gaining more popular understanding these days and may be more familiar for some folks.
As of now there is no available treatment that restores the endothelial integrity of the BBB. Off of the top of my head this study may suggest that more treatments to modulate the inflammsome (roughly—the amount of inflammation in your body) could be beneficial—which sort of tracks since there is some scattered evidence that high dose Omega-3’s help long COVID.
Think of your sleep as reading a series of engaging books, where each book represents a sleep cycle, including chapters of both deep sleep (SWS) and dream sleep (REM). When you finish a book (sleep cycle), you reach a satisfying conclusion to that story arc—this is akin to waking up after a full sleep cycle. You feel refreshed because you’ve concluded the narrative neatly, without interrupting a tense plot twist or leaving a storyline unresolved.
However, just finishing one book doesn’t mean you’ve completed the whole series. If you stop after one book each night, you’re missing out on the depth and development that comes from reading more of the series (accumulating more sleep cycles). Initially, you might feel okay because you’ve concluded a story (cycle) properly, avoiding the grogginess of waking up mid-chapter (mid-cycle). Yet, this approach doesn’t give you the full, enriching experience (or rest) your body and brain need over time.
As days go on, if you continue this pattern, you accumulate a ‘reading debt’—akin to sleep debt. You’ve missed out on the broader, deeper insights and the full narrative arc that only comes from reading (sleeping) the whole series or book. This debt reflects not fully recharging your brain and body, leaving you progressively more tired. While you might feel a temporary refreshment from completing a cycle, without the full, restorative rest of multiple cycles, you’re not truly at 100%—you’re running on the satisfaction of a finished story, not the full restoration that comes from a complete series.
Yeah, it’s about getting enough REM and SWS cycles. The effect decays over time, though. If you time your wake up to a full sleep cycle (around 2.5-3 hours) one night, you may wake up feeling fine. If you do this multiple nights in a row, however, you will build up a REM/SWS debt. So on day one it feels fine, on day two it feels less fine, and on day three you’re dragging.
When my dog died almost a year ago to the day, it was one of the worst things my wife and I have ever gone through. I know that’s proof of my privilege—but I think it’s also proof of how much animals mean to us. They’re pure good. I work a lot of weird shifts; when I come home my wife may not be awake or present, but my dog was always there. It initiated intense, physical grief in both of us.
Lean on any friends or family you have. Post here. Don’t deny how bad you’re hurting, but look for another animal to help after you grieve. I feel like our pets represent different chapters in our life, and when one leaves us a new chapter opens. That chapter may come with a different pet for a different time of your life. We chose to use the closing of our chapter as a transition point—we had a few horrible months at first but ultimately kicked some bad habits we had been building for a while. But where you are right now is horrible, and as another human being I understand to an extent how badly you’re hurting.
I think the loophole is going to stay in place. The hemp lobby has exploded since 2018, and has done a lot to keep the loopholes from closing in even very Red states. In the real world money is what talks, and I think there’s too much money at this point to put the genie back in the bottle.
But that’s my two cents. I could be wrong. Hope I’m not.