I was interested to learn about Rye. I'm definitely though to have to give it a go.

I also started using rye because of this, and it looks great. All I've ever used in the past is virtualenv and venv. Rye is great in that it lets you pin a python version, install packages, auto switches your venv for you. Really nice project that has solved some recent problems for me.

It's a little surprising to see Conda mentioned but not Nix.